drugset / Trial / NCT00789464

Probiotics for Girls With Recurring Urinary Tract Infections

NCT00789464 ↗

Phase 2 Withdrawn Baylor College of Medicine
RandomizedParallel-groupTriple-blindTreatment

Summary

Probiotics are dietary supplements containing potentially beneficial bacterial strains such as Lactobacillus. The safety of oral administration of probiotics has been demonstrated in hundreds of studies using adults over the last 30 years. Very few studies have been conducted with children. UTI in girls occur when virulent bacteria migrate from the rectum and colonize the vagina and peri-urethral mucosa, thus gaining access to the bladder. This study will randomize girls to ARM A (probiotics + placebo) and ARM B (antibiotics + placebo) to determine if UTIs are decreased when the probiotics are given.

Timeline

Start
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Primary completion
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Completion
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Outcome

Outcome not reported

Stopped: “Withdrawn by PI”

Drugs

EvaluationDrugModalityDoseRoute
Subject trimethoprim/sulfamethoxazole Unknown 2 mg/kg Oral