drugset / Trial / NCT00790114
Determine the Effect of Multiple Doses of AZD7325, CYP Study
RandomizedSingle-groupQuadruple-blind
Summary
To determine the effects of repeated doses of AZD7325 on the pharmacokinetic profile of a CYP3A4 substrate (midazolam and its 1' hydroxy metabolite) and a CYP1A2 substrate (caffeine and its paraxanthine \[3-desmethyl\] metabolite).
Timeline
- Start
- 2008-07
- Primary completion
- 2008-09
- Completion
- 2008-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | AZD7325 | Small molecule | — | Oral |
| Subject | Caffeine | Small molecule | — | — |
| Subject | Midazolam | Small molecule | — | — |
Indications
No indication recorded.