Moderate to Severe Plaque Psoriasis With Scalp Involvement

Summary

The purpose of this study is to determine if etanercept is effective in the treatment of scalp involvement in moderate to severe plaque psoriasis.

Timeline

Start

2008-10

Primary completion

2010-01

Completion

2010-03

Outcome

Met primary endpoint

registry analysis (superiority or other test); Placebo BIW/Etanercept 50 mg BIW vs Etanercept 50 mg BIW/Etanercept 50 mg QW; p <0.0001; van Elteren's test NCT00791765 ↗

Publications

• Background Bagel J, Lynde C, Tyring S, Kricorian G, Shi Y, Klekotka P. Moderate to severe plaque psoriasis with scalp involvement: a randomized, double-blind, placebo-controlled study of etanercept. J Am Acad Dermatol. 2012 Jul;67(1):86-92. doi: 10.1016/j.jaad.2011.07.034. Epub 2011 Oct 20.
• Background Tyring S, Bagel J, Lynde C, Klekotka P, Thompson EH, Gandra SR, Shi Y, Kricorian G. Patient-reported outcomes in moderate-to-severe plaque psoriasis with scalp involvement: results from a randomized, double-blind, placebo-controlled study of etanercept. J Eur Acad Dermatol Venereol. 2013 Jan;27(1):125-8. doi: 10.1111/j.1468-3083.2011.04394.x. Epub 2011 Dec 21. No abstract available.

Drugs

Indications