Prophylactic Dimenhydrinate for Intraoperative Nausea and Vomiting

NCT00791960 ↗

Completed 149 enrolled Samuel Lunenfeld Research Institute, Mount Sinai Hospital

RandomizedParallel-groupQuadruple-blindTreatment

Summary

The purpose of this study will be to determine whether an intravenous dose of dimenhydrinate (also known as Gravol), given before the induction of spinal anesthesia, will decrease the incidence of intraoperative nausea and vomiting in patients undergoing Cesarean delivery. This medication is commonly given during and after the surgery if required, but it is not known whether a preventative dose will decrease the overall incidence of these side effects.

Timeline

Start: 2008-11
Primary completion: 2009-09
Completion: 2009-09

Publications

Griffiths JD, Gyte GM, Popham PA, Williams K, Paranjothy S, Broughton HK, Brown HC, Thomas J. Interventions for preventing nausea and vomiting in women undergoing regional anaesthesia for caesarean section. Cochrane Database Syst Rev. 2021 May 18;5(5):CD007579. doi: 10.1002/14651858.CD007579.pub3.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Dimenhydrinate	Small molecule	25 mg	Intravenous

Indications

No indication recorded.