drugset / Trial / NCT00794638

A Phase I Clinical Trial of SyB L-0501 in Combination With Rituximab to Patients With Aggressive B-cell Non-Hodgkin's Lymphoma

NCT00794638

Phase 1 Completed 9 enrolled SymBio Pharmaceuticals
Non-randomizedSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to assess the safety of SyB L-0501 in combination with Rituximab to patients with aggressive B-cell non-Hodgkin's lymphoma, and to explore the recommended dose for the Phase II clinical trial.

Timeline

Start
2008-11
Primary completion
2010-03
Completion
2010-05

Drugs

EvaluationDrugModalityDoseRoute
Subject Bendamustine Small molecule 90 mg/m2
Subject Bendamustine Small molecule 120 mg/m2
Background Rituximab Monoclonal antibody 375 mg/m2