drugset / Trial / NCT00798278

Urokinase Versus Video-assisted Thoracoscopic to Treat Complicated Parapneumonic Empyema in Childhood

NCT00798278

Phase 3 Completed 200 enrolled Spanish Society of Pediatric Surgery
RandomizedParallel-groupOpen-labelTreatment

Summary

A great controversy exists about which is the best method to perform the evacuation of the collection. The purpose of this study is to evaluate which is the best initial treatment to drain complicated parapneumonic empyema (stages II and III) in children: the present study raises a hypothesis of equivalence between both arms of treatment (chest drainage plus intrapleural urokinase or videothoracoscopic debridement).

Timeline

Start
2008-07
Primary completion
2010-09
Completion
2010-09

Drugs

EvaluationDrugModalityDoseRoute
Subject Urokinase Protein / enzyme biologic Other

Indications