drugset / Trial / NCT00799604
Clevidipine Bolus Administration in the Treatment of Hypertensive Patients Undergoing Cardiac Surgery (SPRINT)
NaSingle-groupOpen-labelTreatment
Summary
This study was designed to evaluate the pharmacodynamics of a bolus dosing regimen of clevidipine, a vascular-selective L-type calcium channel antagonist, for the management of blood pressure in cardiac surgery patients, as well as to evaluate the efficacy, safety and pharmacokinetics of clevidipine after bolus administration.
Timeline
- Start
- 2008-11
- Primary completion
- 2009-10
- Completion
- 2009-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Clevidipine | Small molecule | 125 ug | Intravenous |
| Subject | Clevidipine | Small molecule | 250 ug | Intravenous |
| Subject | Clevidipine | Small molecule | 500 ug | Intravenous |