drugset / Trial / NCT00800579
Trial to Assess the Safety, Tolerability and Pharmacokinetics of GS-9411 in Healthy Male Volunteers
RandomizedCrossoverQuadruple-blindTreatment
Summary
The purpose of this study is to evaluate the safety and tolerability of escalating doses of GS-9411 in healthy male volunteers. GS-9411 is a sodium channel inhibitor, that may restore airway hydration and mucociliary clearance in the lung.
Timeline
- Start
- 2008-11
- Primary completion
- 2009-02
- Completion
- 2009-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | GS-9411 | Small molecule | 0.6 mg | Inhaled |
| Subject | GS-9411 | Small molecule | 1.2 mg | Inhaled |
| Subject | GS-9411 | Small molecule | 2.4 mg | Inhaled |