drugset / Trial / NCT00801294

A Phase II Trial of Weekly Alternating Sequential Administration of BIBF 1120 and BIBW 2992 in Patients With Advanced Colorectal Cancer

NCT00801294

Phase 2 Completed 46 enrolled Boehringer Ingelheim
Parallel-groupTreatment

Summary

The primary objective of this trial is to explore the overall objective best response rate and the rate of non-progression at 16 weeks of sequential, alternating weekly administration of BIBF 1120 and BIBW 2992 in patients with metastatic CRC based on the RECIST criteria.

Timeline

Start
2006-07-01
Primary completion
2007-11-01
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Afatinib Small molecule
Subject Nintedanib Small molecule

Indications