drugset / Trial / NCT00803348

Continuous Femoral Nerve Blockade and Readiness to Discharge Following Total Knee Arthroplasty

NCT00803348 ↗

Completed 99 enrolled University Health Network, Toronto
RandomizedParallel-groupDouble-blindTreatment

Summary

Patients undergoing total knee arthroscopy (knee replacement) surgery usually receive a femoral nerve block as part of their anesthetic care. Some centers administer the block with a single shot of local anesthetic, which wears off several hours after surgery. Other centers administer the block with a single shot followed by continuous infusion of local anesthetic, typically for 2 to 5 days after surgery. The latter method, though good for pain control, may result in decreased mobility (while the anesthetic is still active), longer hospital stays, and greater risk of falls. This study will see if using a lower concentration of local anesthetic for the continuous femoral nerve block or only the initial single-shot dose will result in increased mobility and shorter hospital stays.

Timeline

Start
2009-05
Primary completion
2011-10
Completion
2011-10

Drugs

EvaluationDrugModalityDoseRoute
Comparator Ropivacaine Other / unclassified 0.1 % Other
Comparator Ropivacaine Other / unclassified 0.2 % Other
Comparator Ropivacaine Other / unclassified 0.375 % Other

Indications