drugset / Trial / NCT00803634

Clevidipine in the Treatment of Blood Pressure in Patients With Acute Heart Failure (PRONTO)

NCT00803634

Phase 3 Completed 117 enrolled The Medicines Company
RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study was to evaluate the efficacy and safety of intravenous (IV) clevidipine as compared with standard of care IV antihypertensive agents for blood pressure (BP) lowering in patients with acute heart failure and elevated BP.

Timeline

Start
2008-12
Primary completion
2012-02
Completion
2012-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Clevidipine Small molecule
Comparator Diltiazem Small molecule Intravenous
Comparator Isosorbide Dinitrate Other / unclassified Intravenous
Comparator Nicardipine Small molecule Intravenous
Comparator Nitroglycerin Unknown Intravenous
Comparator Sodium Nitroprusside Unknown Intravenous