drugset
drugset / Trial / NCT00804219

Humoral and Cellular Immunity of Low and High-responders After Tick-borne Encephalitis Vaccination

NCT00804219 ↗

Phase 4 Completed 67 enrolled Medical University of Vienna
Non-randomizedParallel-groupOpen-labelBasic science

Summary

The phenomenon of no- and low-responsiveness has been described after applications of different vaccines (e.g. hepatitis B, TBE) and is concerning about 2-10% of the vaccinees. The aim of this project is to investigate the humoral and cellular immune responses of low-responders after TBE vaccination in order to find parameters regarding immunoregulation against TBE. It is of interest if non-responsiveness is a general immunological deficit of a distinct patient group or if it is a antigen-specific phenomenon.

Timeline

Start
2008-12
Primary completion
2010-11
Completion
2010-11

Drugs

EvaluationDrugModalityDoseRoute
Subject FSME-IMMUN Vaccine 0.5 ml Intramuscular
Background Inflexal Vaccine 0.5 ml Intramuscular

Indications

tick-borne encephalitis