drugset / Trial / NCT00804830
Avastin and Doxorubicin Postoperatively for Patients With Anaplastic Thyroid Cancer
NaSingle-groupOpen-labelTreatment
Summary
Anaplastic Thyroid Cancer is a very aggressive disease. The investigators believe that angiogenesis is very important for these tumors to progress. Preclinical data is suggesting this. This is why we we prospectively want to treat these patients with avastin (and doxorubicin). However, local control is of major concern. Therefore, patients are initially treated with hyperfractionated radiotherapy and undergo surgery. Then they can enter this study.
Timeline
- Start
- 2008-04
- Primary completion
- 2012-12
- Completion
- 2014-12
Outcome
Outcome not reported
Stopped: “lack of response”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Bevacizumab | Monoclonal antibody | 15 mg/kg | — |
| Subject | Doxorubicin | Other / unclassified | 20 mg | — |