drugset / Trial / NCT00804830

Avastin and Doxorubicin Postoperatively for Patients With Anaplastic Thyroid Cancer

NCT00804830 ↗

Phase 2 Terminated 15 enrolled Region Skane
NaSingle-groupOpen-labelTreatment

Summary

Anaplastic Thyroid Cancer is a very aggressive disease. The investigators believe that angiogenesis is very important for these tumors to progress. Preclinical data is suggesting this. This is why we we prospectively want to treat these patients with avastin (and doxorubicin). However, local control is of major concern. Therefore, patients are initially treated with hyperfractionated radiotherapy and undergo surgery. Then they can enter this study.

Timeline

Start
2008-04
Primary completion
2012-12
Completion
2014-12

Outcome

Outcome not reported

Stopped: “lack of response”

Drugs

EvaluationDrugModalityDoseRoute
Subject Bevacizumab Monoclonal antibody 15 mg/kg —
Subject Doxorubicin Other / unclassified 20 mg —