Evaluate the Onset of Action of SKY0402 Following Local Infiltration in Healthy Volunteers

Phase 1 Completed 128 enrolled Pacira Pharmaceuticals, Inc

RandomizedCrossoverSingle-blindSupportive care

Summary

Given as a single perioperative injection, SKY0402 could provide adequate, continuous, and extended pain relief that could greatly simplify postoperative pain management, reduce the need for repeated administration, and minimize episodes of breakthrough pain.

Timeline

Start: 2008-10
Primary completion: 2009-02
Completion: 2009-02

Publications

Apseloff G, Onel E, Patou G. Time to onset of analgesia following local infiltration of liposome bupivacaine in healthy volunteers: a randomized, single-blind, sequential cohort, crossover study. Int J Clin Pharmacol Ther. 2013 May;51(5):367-73. doi: 10.5414/CP201775.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	SKY0402	Unknown	40 mg	Other

Indications

No indication recorded.