drugset / Trial / NCT00807989
The Efficacy and Safety of Low Dose Combination of LTG and VPA Compared to CBZ Monotherapy
RandomizedParallel-groupOpen-labelTreatment
Summary
To evaluate the efficacy of usual monotherapy and low dose combination of Lamotrigine and Valproate. Low dose combination may be more effective and tolerable because they are low dose and VPA reduce Lamotrigine metabolism.
Timeline
- Start
- 2008-03
- Primary completion
- 2012-05
- Completion
- 2012-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Carbamazepine | Small molecule | — | — |
| Subject | Lamotrigine | Small molecule | — | — |
| Subject | Valproate | Small molecule | — | — |