Evaluation of Analgesia With EMLA and Glucose Oral Solution

Phase 4 Completed 60 enrolled Federal University of Minas Gerais

RandomizedParallel-groupQuadruple-blindSupportive care

Summary

In this randomized controlled study the investigators intended to compare analgesic effects of EMLA and/or oral glucose in 60 preterm neonate during arterial function and PICC installation.

Timeline

Start: 2008-11
Primary completion: 2009-12
Completion: 2009-12

Publications

Background Lehr VT, Taddio A. Topical anesthesia in neonates: clinical practices and practical considerations. Semin Perinatol. 2007 Oct;31(5):323-9. doi: 10.1053/j.semperi.2007.07.008.
Background Taddio A, Ohlsson A, Einarson TR, Stevens B, Koren G. A systematic review of lidocaine-prilocaine cream (EMLA) in the treatment of acute pain in neonates. Pediatrics. 1998 Feb;101(2):E1. doi: 10.1542/peds.101.2.e1.
Background Deshmukh LS, Udani RH. Analgesic effect of oral glucose in preterm infants during venipuncture--a double-blind, randomized, controlled trial. J Trop Pediatr. 2002 Jun;48(3):138-41. doi: 10.1093/tropej/48.3.138.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	EMLA	Unknown	0.5 g	Topical

Indications

No indication recorded.