drugset / Trial / NCT00811902
Efficacy, Safety, and Tolerability of Nerispirdine in Patients With Multiple Sclerosis
RandomizedParallel-groupTriple-blindTreatment
Summary
The primary objective is to assess the activity of nerispirdine in improving the ability to walk, in patients with multiple sclerosis (MS). Secondary objectives: * To assess other measures of walking ability, tiredness, and lower limb muscular strength, spasticity, clinical assessment by subject and clinical assessment of change by the Study Investigator * To assess the safety and tolerance of nerispirdine * To evaluate the pharmacokinetics (PK) parameters of nerispirdine
Timeline
- Start
- 2008-12
- Primary completion
- 2010-03
- Completion
- 2010-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Nerispirdine | Small molecule | 50 mg | Oral |
| Subject | Nerispirdine | Small molecule | 100 mg | Oral |
| Subject | Nerispirdine | Small molecule | 200 mg | Oral |