drugset / Trial / NCT00811902

Efficacy, Safety, and Tolerability of Nerispirdine in Patients With Multiple Sclerosis

NCT00811902 ↗

Phase 2 Completed 405 enrolled Sanofi
RandomizedParallel-groupTriple-blindTreatment

Summary

The primary objective is to assess the activity of nerispirdine in improving the ability to walk, in patients with multiple sclerosis (MS). Secondary objectives: * To assess other measures of walking ability, tiredness, and lower limb muscular strength, spasticity, clinical assessment by subject and clinical assessment of change by the Study Investigator * To assess the safety and tolerance of nerispirdine * To evaluate the pharmacokinetics (PK) parameters of nerispirdine

Timeline

Start
2008-12
Primary completion
2010-03
Completion
2010-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Nerispirdine Small molecule 50 mg Oral
Subject Nerispirdine Small molecule 100 mg Oral
Subject Nerispirdine Small molecule 200 mg Oral

Indications