drugset

drugset / Trial / NCT00812396

Biomarkers of Muscle Anabolism (MK-0000-082)

NCT00812396 ↗

Phase 1 Completed 30 enrolled Merck Sharp & Dohme LLC

RandomizedParallel-groupSingle-blindDiagnostic

Summary

This study will evaluate the ability of comparative proteomics to identify early biomarkers of muscle anabolism.

Timeline

Start: 2007-11
Primary completion: 2008-02
Completion: 2008-02

Publications

Results Chen F, Lam R, Shaywitz D, Hendrickson RC, Opiteck GJ, Wishengrad D, Liaw A, Song Q, Stewart AJ, Cummings CE, Beals C, Yarasheski KE, Reicin A, Ruddy M, Hu X, Yates NA, Menetski J, Herman GA. Evaluation of early biomarkers of muscle anabolic response to testosterone. J Cachexia Sarcopenia Muscle. 2011 Mar;2(1):45-56. doi: 10.1007/s13539-011-0021-y. Epub 2011 Feb 26.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Testosterone	Small molecule	200 mg	Intramuscular
Comparator	Testosterone	Small molecule	600 mg	Intramuscular

Indications

No indication recorded.