drugset

drugset / Trial / NCT00812864

Pharmacokinetic Study of Capecitabine in Elderly Cancer Patient (≥ 75 Years)

NCT00812864 ↗

Phase 4 Completed 20 enrolled University Hospital, Limoges

Non-randomizedSingle-groupOpen-labelDiagnostic

Summary

The aim of the study is to determine blood concentration evolution of capecitabine and its active metabolites, in elderly patient 75 years and more.

Timeline

Start: 2009-01
Primary completion: 2011-10
Completion: 2012-11

Publications

Results Daher Abdi Z, Lavau-Denes S, Premaud A, Urien S, Sauvage FL, Martin J, Leobon S, Marquet P, Tubiana-Mathieu N, Rousseau A. Pharmacokinetics and exposure-effect relationships of capecitabine in elderly patients with breast or colorectal cancer. Cancer Chemother Pharmacol. 2014 Jun;73(6):1285-93. doi: 10.1007/s00280-014-2466-0. Epub 2014 May 7.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Capecitabine	Small molecule	1250 mg/m2	Oral

Indications