drugset / Trial / NCT00814060

Study Evaluating TwoTablet Formulations of Neratinib (HKI-272)

NCT00814060

Phase 1 Completed 24 enrolled Puma Biotechnology, Inc.
RandomizedCrossoverOpen-labelTreatment

Summary

This study will examine the bioavailability (the rate and extent to which the active ingredient or active moiety is absorbed from a drug product and becomes available at the site of action) of two tablet formulations of Neratinib (HKI-272) compared to the capsule formulation.

Timeline

Start
2009-01
Primary completion
2009-03
Completion
2009-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Neratinib Small molecule 40 mg
Subject Neratinib Small molecule 80 mg
Subject Neratinib Small molecule 240 mg

Indications

No indication recorded.