Effect of Oral Galactose on Focal Segmental Glomerulosclerosis (FSGS) Permeability Factor

Summary

This study is a proof-of-concept clinical study designed to test the hypothesis that oral administration of galactose can lower the level of a circulating factor that increases glomerular permeability to albumin in patients with resistant FSGS.

Timeline

Start

2008-12

Primary completion

2009-12

Completion

2009-12

Publications

• Background Trachtman H, Greenbaum LA, McCarthy ET, Sharma M, Gauthier BG, Frank R, Warady B, Savin VJ. Glomerular permeability activity: prevalence and prognostic value in pediatric patients with idiopathic nephrotic syndrome. Am J Kidney Dis. 2004 Oct;44(4):604-10.

Drugs

Indications