drugset / Trial / NCT00816790
Standard Vs Adjusted Dosing of Piperacillin/Tazobactam in Acute Renal Failure and Septic Shock
RandomizedParallel-groupDouble-blindTreatment
Summary
The objective of this study is to determine the feasibility of conducting a large scale randomized controlled trial comparing standard and renally adjusted dosage of antibiotics in the septic shock patients with acute renal dysfunction. We will use Piperacillin as the prototype antibiotic in our study.
Timeline
- Start
- 2009-01
- Primary completion
- 2011-05
- Completion
- 2011-06
Outcome
Outcome not reported
Stopped: “Study stopped because of study personel movement to another institution.”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Piperacillin/Tazobactam | Unknown | 2.25 g | Intravenous |
| Subject | Piperacillin/Tazobactam | Unknown | 3.375 g | Intravenous |
| Subject | Piperacillin/Tazobactam | Unknown | 4.5 g | Intravenous |