drugset / Trial / NCT00820989

Inflammation and the Host Response to Injury (In Healthy Volunteers)

NCT00820989

Phase 1 Completed 116 enrolled Rutgers, The State University of New Jersey
Non-randomizedSingle-groupOpen-label

Summary

The body's immune response to injury or infection is very complex.Endotoxin is a man-made substance, which causes the body to "mimic" sickness (fever,chills, and achiness)for a few hours. This study is designed to determine whether certain proteins, genetics, or heart rate variability change affects the body's response to endotoxin.

Timeline

Start
2000-02
Primary completion
2011-02
Completion
2011-02

Drugs

EvaluationDrugModalityDoseRoute
Subject Lipopolysaccharide Other / unclassified 2 ng Intravenous