Effect of Smoking, Abstention and Nicotine Replacement Therapy on Wound Healing

Completed 78 enrolled Bispebjerg Hospital The Danish Medical Research Council · collab

RandomizedParallel-groupQuadruple-blindBasic science

Summary

The aim was to determine the wound healing capacity in healthy never smokers and smokers who continue to smoke, or quit smoking using transdermal nicotine patch versus placebo patch.

Timeline

Start: 2000-08
Primary completion: 2000-12
Completion: 2001-01

Publications

Results Sorensen LT, Karlsmark T, Gottrup F. Abstinence from smoking reduces incisional wound infection: a randomized controlled trial. Ann Surg. 2003 Jul;238(1):1-5. doi: 10.1097/01.SLA.0000074980.39700.31.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Nicotine	Unknown	25 mg	Other

Indications

No indication recorded.