drugset / Trial / NCT00826748
Effect of Inhaled Steroids on Gene Expression in the Lungs - 2
RandomizedFactorialOpen-labelOther
Summary
The purpose of this study is to assess the effect of inhaled beclomethasone (an inhaled corticosteroid) on the pattern of the lung airway epithelium and alveolar macrophages gene expression of healthy smokers. We hypothesize that the administration of beclomethasone will result in reversibility of some of the airway epithelium and alveolar macrophage gene expression changes induced by cigarette smoking.
Timeline
- Start
- 2010-11
- Primary completion
- 2014-12
- Completion
- 2014-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Beclomethasone | Small molecule | 320 ug | Inhaled |