drugset / Trial / NCT00826748

Effect of Inhaled Steroids on Gene Expression in the Lungs - 2

NCT00826748

Phase 4 Terminated 24 enrolled Weill Medical College of Cornell University
RandomizedFactorialOpen-labelOther

Summary

The purpose of this study is to assess the effect of inhaled beclomethasone (an inhaled corticosteroid) on the pattern of the lung airway epithelium and alveolar macrophages gene expression of healthy smokers. We hypothesize that the administration of beclomethasone will result in reversibility of some of the airway epithelium and alveolar macrophage gene expression changes induced by cigarette smoking.

Timeline

Start
2010-11
Primary completion
2014-12
Completion
2014-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Beclomethasone Small molecule 320 ug Inhaled