drugset / Trial / NCT00827177

Dose Escalation Study of ARQ 197 in Combination With Sorafenib in Adult Patients With Advanced Solid Tumors

NCT00827177

Phase 1 Completed 87 enrolled ArQule, Inc.
NaSingle-groupOpen-labelTreatment

Summary

This is an open-label, dose-escalation study of ARQ 197 administered orally in combination with sorafenib.

Timeline

Start
2009-09
Primary completion
2012-09
Completion
2013-05

Drugs

EvaluationDrugModalityDoseRoute
Subject Sorafenib Small molecule 200 mg
Subject Sorafenib Small molecule 400 mg
Subject Tivantinib Small molecule 240 mg Oral
Subject Tivantinib Small molecule 360 mg Oral

Indications