Pharmacokinetic Properties of Lorcaserin in Subjects With Hepatic Impairment

Phase 1 Completed 24 enrolled Eisai Inc.

NaSingle-groupOpen-labelOther

Summary

The purpose of this study is to evaluate and establish whether lorcaserin dose adjustment is required in patients with mild or moderate hepatic impairment.

Timeline

Start: 2008-08
Primary completion: 2008-12
Completion: 2008-12

Publications

Christopher RJ, Morgan ME, Tang Y, Anderson C, Sanchez M, Shanahan W. Pharmacokinetics and Tolerability of Lorcaserin in Special Populations: Elderly Patients and Patients with Renal or Hepatic Impairment. Clin Ther. 2017 Apr;39(4):837-848.e7. doi: 10.1016/j.clinthera.2017.03.004. Epub 2017 Mar 30.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Lorcaserin	Small molecule	10 mg	—

Indications

No indication recorded.