drugset

drugset / Trial / NCT00829114

Interactions Between Antiretrovirals (ARVs) and Combined Oral Contraceptives (COCs)

NCT00829114 ↗

Phase 4 Completed 370 enrolled FHI 360 Makerere University · collab RHRU National Office, University of Witwatersand, Johannesburg · collab United States Agency for International Development (USAID) · collab

Non-randomizedParallel-groupOpen-labelPrevention

Summary

Non-randomized, comparative study (1:1 allocation) to study interactions between nevirapine-containing antiretroviral therapies and combined oral contraceptive pills.

Timeline

Start: 2009-03
Primary completion: 2011-04
Completion: 2011-04

Publications

Nanda K, Delany-Moretlwe S, Dube K, Lendvay A, Kwok C, Molife L, Nakubulwa S, Edward VA, Mpairwe B, Mirembe FM. Nevirapine-based antiretroviral therapy does not reduce oral contraceptive effectiveness. AIDS. 2013 Oct;27 Suppl 1:S17-25. doi: 10.1097/QAD.0000000000000050.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	LEVOGESTREL	Unknown	150 ug	Oral
Comparator	ethinyl estradiol	Small molecule	30 ug	Oral

Indications