Fluticasone/Salmeterol (FP/SM) Versus Double the Dose Fluticasone (FP) in Patients With Mild to Moderate Asthma

Summary

The purpose of this study is to compare the effects of Fluticasone/ salmeterol combination and double the dose of fluticasone on airway hyper-responsiveness to methacholine in a randomised, double blind, double dummy, cross-over trial.

Timeline

Start

2009-04

Primary completion

2010-05

Completion

2010-05

Publications

• Results Clearie KL, McKinlay L, Williamson PA, Lipworth BJ. Fluticasone/Salmeterol combination confers benefits in people with asthma who smoke. Chest. 2012 Feb;141(2):330-338. doi: 10.1378/chest.11-0392. Epub 2011 Jun 2.

Drugs

Indications