drugset / Trial / NCT00830960
A Comparison of Antiplatelet Therapies in Asian Subjects With Acute Coronary Syndrome
RandomizedParallel-groupTriple-blindTreatment
Summary
The study will compare the safety and efficacy of prasugrel, administered at different doses with clopidogrel in the treatment of Asian participants with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention.
Timeline
- Start
- 2009-02
- Primary completion
- 2010-06
- Completion
- 2010-06
Outcome
Met primary endpoint
registry Prasugrel 60-mg LD Primary vs Clopidogrel 300-mg LD Primary; p <0.0001; Least Square (LS) Mean Difference in PRU -183 (95% CI -229 to -137) NCT00830960 ↗
registry Prasugrel 30/5 Primary vs Clopidogrel 300/75 Primary; p = 0.0020; LS mean difference in PRU -51 (95% CI -83 to -19) NCT00830960 ↗
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Clopidogrel | Small molecule | 75 mg | Oral |
| Subject | Prasugrel | Small molecule | 5 mg | Oral |
| Subject | Prasugrel | Small molecule | 7.5 mg | Oral |
| Subject | Prasugrel | Small molecule | 10 mg | Oral |