drugset

drugset / Trial / NCT00836199

NicVAX/Placebo as an Aid for Smoking Cessation

NCT00836199 ↗

Phase 3 Completed 1000 enrolled Nabi Biopharmaceuticals National Institute on Drug Abuse (NIDA) · collab

RandomizedParallel-groupQuadruple-blindTreatment

Summary

The purpose of this study is to evaluate NicVAX as an aid to smoking cessation for long term abstinence.

Timeline

Start: 2009-10
Primary completion: 2011-07
Completion: 2011-07

Outcome

Missed primary endpoint

paper NicVAX, failed to meet the primary endpoint in two large phase III studies PMID 22229310 ↗

Publications

Fahim RE, Kessler PD, Fuller SA, Kalnik MW. Nicotine vaccines. CNS Neurol Disord Drug Targets. 2011 Dec;10(8):905-15. doi: 10.2174/187152711799219343.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	NicVAX	Vaccine	—	—

Indications