drugset / Trial / NCT00837928
Bendamustine and Radiation Therapy in Treating Patients With Brain Metastases Caused by Solid Tumors
NaSingle-groupOpen-labelTreatment
Summary
RATIONALE: Drugs used in chemotherapy, such as bendamustine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Stereotactic radiation therapy may be able to send x-rays directly to the tumor and cause less damage to normal tissue. PURPOSE: This phase I trial is studying the side effects and best dose of bendamustine when given together with radiation therapy in treating patients with brain metastases caused by solid tumors.
Timeline
- Start
- 2009-02-19
- Primary completion
- 2015-01-08
- Completion
- 2015-01-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Bendamustine | Small molecule | 40 mg/m2 | Intravenous |
| Subject | Bendamustine | Small molecule | 50 mg/m2 | Intravenous |