drugset / Trial / NCT00837928

Bendamustine and Radiation Therapy in Treating Patients With Brain Metastases Caused by Solid Tumors

NCT00837928

NaSingle-groupOpen-labelTreatment

Summary

RATIONALE: Drugs used in chemotherapy, such as bendamustine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Stereotactic radiation therapy may be able to send x-rays directly to the tumor and cause less damage to normal tissue. PURPOSE: This phase I trial is studying the side effects and best dose of bendamustine when given together with radiation therapy in treating patients with brain metastases caused by solid tumors.

Timeline

Start
2009-02-19
Primary completion
2015-01-08
Completion
2015-01-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Bendamustine Small molecule 40 mg/m2 Intravenous
Subject Bendamustine Small molecule 50 mg/m2 Intravenous