drugset / Trial / NCT00838058
A Study in Normal Healthy People, Testing Different Versions of a Pill That Will be Used to Treat Rheumatoid Arthritis.
RandomizedCrossoverOpen-label
Summary
The study will try, in 2 separate parts, each using 12 research subjects, to see how a new form of the pill CE 224,535 gets released into the bloodstream and whether that is affected by food. In each part, subjects will switch among 4 treatment periods to take either different forms of the pill(s) or the same form either after fasting or eating a meal. The second part will only happen depending on whether the sponsor believes it is needed and will use separate subject than the first part.
Timeline
- Start
- 2009-01
- Primary completion
- 2009-03
- Completion
- 2009-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | CE-224,535 | Small molecule | 250 mg | — |
| Subject | CE-224,535 | Small molecule | 500 mg | — |
| Subject | CE-224,535 | Small molecule | 1000 mg | — |