drugset / Trial / NCT00839540
Comparison of Candida Eradication and Serum Cidal Activity of Echinocandins
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this pharmacokinetic (PK) and pharmacodynamic (PD) study is: To study the rate and duration of serum cidal activity of caspofungin (CFG) and micafungin (MFG) against Candida isolates from the subject and against Candida glabrata with varying degrees of caspofungin susceptibilities. This investigation will provide clinicians information supporting the use of caspofungin and micafungin in situations where Candida strains may be a cause of infection.
Timeline
- Start
- 2008-12
- Primary completion
- 2010-05
- Completion
- 2010-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Caspofungin | Other / unclassified | 50 mg | Intravenous |
| Comparator | Micafungin | Peptide | 100 mg | Intravenous |
| Comparator | Micafungin | Peptide | 200 mg | Intravenous |