drugset / Trial / NCT00839540

Comparison of Candida Eradication and Serum Cidal Activity of Echinocandins

NCT00839540

RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this pharmacokinetic (PK) and pharmacodynamic (PD) study is: To study the rate and duration of serum cidal activity of caspofungin (CFG) and micafungin (MFG) against Candida isolates from the subject and against Candida glabrata with varying degrees of caspofungin susceptibilities. This investigation will provide clinicians information supporting the use of caspofungin and micafungin in situations where Candida strains may be a cause of infection.

Timeline

Start
2008-12
Primary completion
2010-05
Completion
2010-05

Drugs

EvaluationDrugModalityDoseRoute
Comparator Caspofungin Other / unclassified 50 mg Intravenous
Comparator Micafungin Peptide 100 mg Intravenous
Comparator Micafungin Peptide 200 mg Intravenous

Indications