drugset / Trial / NCT00841971
Anidulafungin Versus Fluconazole for the Prevention of Fungal Infections in Liver Transplant Recipients
RandomizedParallel-groupTriple-blindPrevention
Summary
The purpose of this study is to compare the efficacy of anidulafungin versus fluconazole for the prevention of fungal diseases in liver transplant recipients
Timeline
- Start
- 2010-02
- Primary completion
- 2013-07
- Completion
- 2014-05
Publications
- Results Winston DJ, Limaye AP, Pelletier S, Safdar N, Morris MI, Meneses K, Busuttil RW, Singh N. Randomized, double-blind trial of anidulafungin versus fluconazole for prophylaxis of invasive fungal infections in high-risk liver transplant recipients. Am J Transplant. 2014 Dec;14(12):2758-64. doi: 10.1111/ajt.12963. Epub 2014 Nov 6.
- Singh N, Winston DJ, Limaye AP, Pelletier S, Safdar N, Morris MI, Meneses K, Busuttil RW, Wagener MM, Wheat LJ. Performance Characteristics of Galactomannan and beta-d-Glucan in High-Risk Liver Transplant Recipients. Transplantation. 2015 Dec;99(12):2543-50. doi: 10.1097/TP.0000000000000763.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Anidulafungin | Other / unclassified | 100 mg | Intravenous |
| Comparator | Fluconazole | Small molecule | 400 mg | Intravenous |