Evaluation of the Efficacy and Tolerability of Clobetasol Propionate Foam Compared to Vehicle Foam
Summary
The purpose of the study is to compare the efficacy and safety of Clobetasol propionate to that of its Vehicle in the treatment of mild to moderate plaque-type psoriasis.
Timeline
- Start
- 2007-11
- Primary completion
- 2007-12
- Completion
- 2008-01
Outcome
Mixed primary results
registry analysis (superiority or other test); Olux-E Foam vs Vehicle Foam; p = 0.1269; Fisher Exact; note: P-value for Week 1 NCT00842153 ↗
registry NUMBER Olux-E Foam: Week 2, n=26, 30: 19 participants NCT00842153 ↗
registry NUMBER Vehicle Foam: Week 2, n=26, 30: 3 participants NCT00842153 ↗
registry analysis (superiority or other test); Olux-E Foam vs Vehicle Foam; p <0.0001; Chi-squared; note: P-value for Week 2 NCT00842153 ↗
registry NUMBER Olux-E Foam: Week 4, n=27, 28: 12 participants NCT00842153 ↗
registry NUMBER Vehicle Foam: Week 4, n=27, 28: 2 participants NCT00842153 ↗
registry analysis (superiority or other test); Olux-E Foam vs Vehicle Foam; p = 0.0015; Chi-squared; note: P-value for Week 4 NCT00842153 ↗
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | clobetasol propionate | Small molecule | — | Topical |