Efficacy and Safety of Oral Isotretinoin for Cutaneous Photodamage

Summary

This is a randomized, comparative, single evaluator-blinded trial to evaluate clinical, histological and immunohistochemical effects of oral isotretinoin plus moisturizer sunscreen as compared to the use of 0,05% tretinoin cream plus moisturizer sunscreen for the treatment of photodamage on face and forearms. Main oral isotretinoin safety parameters will also be analyzed, as well as adverse events related to topical products.

Timeline

Start

2009-05

Primary completion

2009-12

Completion

2010-08

Drugs

Indications