drugset / Trial / NCT00843024
Migraine Study in Adolescent Patients
RandomizedParallel-groupDouble-blindTreatment
Summary
This study was designed to determine how well the combination medication, sumatriptan and naproxen sodium, treats migraine headache in adolescents 12-17 years old
Timeline
- Start
- 2008-12
- Primary completion
- 2010-05
- Completion
- 2010-06
Publications
- Background Brandes JL, Kudrow D, Stark SR, O'Carroll CP, Adelman JU, O'Donnell FJ, Alexander WJ, Spruill SE, Barrett PS, Lener SE. Sumatriptan-naproxen for acute treatment of migraine: a randomized trial. JAMA. 2007 Apr 4;297(13):1443-54. doi: 10.1001/jama.297.13.1443.
- Derosier FJ, Lewis D, Hershey AD, Winner PK, Pearlman E, Rothner AD, Linder SL, Goodman DK, Jimenez TB, Granberry WK, Runken MC. Randomized trial of sumatriptan and naproxen sodium combination in adolescent migraine. Pediatrics. 2012 Jun;129(6):e1411-20. doi: 10.1542/peds.2011-2455. Epub 2012 May 14.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Naproxen | Small molecule | 60 mg | — |
| Subject | Naproxen | Small molecule | 180 mg | — |
| Subject | Naproxen | Small molecule | 500 mg | — |
| Subject | Sumatriptan | Unknown | 10 mg | — |
| Subject | Sumatriptan | Unknown | 30 mg | — |
| Subject | Sumatriptan | Unknown | 85 mg | — |