Controlled Study of the Ability of a Smokefree Tobacco Product to Increase the Quit Rate Among Cigarette Smokers

Phase 4 Completed 250 enrolled Swedish Match AB

RandomizedParallel-groupQuadruple-blindTreatment

Summary

The study aims to assess if use of a low-nitrosamine, Swedish, smokefree tobacco product for oral use ("snus") can increase the quit rate among cigarette smokers who wish to stop smoking

Timeline

Start: 2009-02
Primary completion: 2010-06
Completion: 2010-06

Outcome

Missed primary endpoint

paper Although the cessation rates generally were low and, at 28 weeks, did not differ between active and placebo PMID 21994343 ↗

Publications

Results Fagerstrom K, Rutqvist LE, Hughes JR. Snus as a smoking cessation aid: a randomized placebo-controlled trial. Nicotine Tob Res. 2012 Mar;14(3):306-12. doi: 10.1093/ntr/ntr214. Epub 2011 Oct 12.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	snus	Unknown	0.5 g	Oral
Subject	snus	Unknown	1 g	Oral

Indications

No indication recorded.