drugset / Trial / NCT00844064

Safety and Tolerability of AP 12009, Administered I.V. in Patients With Advanced Tumors Known to Overproduce TGF-beta-2

NCT00844064

Phase 1 Completed 62 enrolled Isarna Therapeutics GmbH
NaSingle-groupOpen-labelTreatment

Summary

In this national Phase I dose-escalation study the safety and tolerability of AP 12009 is evaluated in adult patients with advanced tumors known to overproduce TGF-β2, who are not or no longer amenable to established therapies.

Timeline

Start
2005-01
Primary completion
2011-11
Completion
2011-11

Drugs

EvaluationDrugModalityDoseRoute
Subject trabedersen Antisense oligonucleotide Intravenous