drugset / Trial / NCT00844727
Coxib-inhibition of Duodenal Polyp Growth in FAP
RandomizedParallel-groupDouble-blindTreatment
Summary
Preliminary data indicate a protective effect on the development of duodenal polyps by coxib treatment. The hypothesis of the present study is that normal therapy doses of rofecoxib for 1 year would stop or reverse the development of premalignant adenomatous lesions in the duodenal mucosa of FAP patients.
Timeline
- Start
- 2003-09
- Primary completion
- 2004-04
- Completion
- 2004-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | rofecoxib | Small molecule | 25 mg | — |