drugset / Trial / NCT00844727

Coxib-inhibition of Duodenal Polyp Growth in FAP

NCT00844727

Phase 2/3 Terminated 38 enrolled Oslo University Hospital
RandomizedParallel-groupDouble-blindTreatment

Summary

Preliminary data indicate a protective effect on the development of duodenal polyps by coxib treatment. The hypothesis of the present study is that normal therapy doses of rofecoxib for 1 year would stop or reverse the development of premalignant adenomatous lesions in the duodenal mucosa of FAP patients.

Timeline

Start
2003-09
Primary completion
2004-04
Completion
2004-04

Drugs

EvaluationDrugModalityDoseRoute
Comparator rofecoxib Small molecule 25 mg

Indications