drugset / Trial / NCT00845351

Preoperative Bexarotene Treatment for Cushing's Disease

NCT00845351

Phase 1/2 Unknown 6 enrolled University of Virginia
NaSingle-groupOpen-label

Summary

The objective of this pilot study is to establish the safety and tolerability of short-term therapy with bexarotene in patient's with Cushing's disease, and study the clinical, biochemical, and cellular effects of a preoperative five-day course of bexarotene in these patients before undergoing transsphenoidal surgery.

Timeline

Start
2008-11
Primary completion
2011-12
Completion
2011-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Bexarotene Small molecule 300 mg/m2