drugset / Trial / NCT00845351
Preoperative Bexarotene Treatment for Cushing's Disease
NaSingle-groupOpen-label
Summary
The objective of this pilot study is to establish the safety and tolerability of short-term therapy with bexarotene in patient's with Cushing's disease, and study the clinical, biochemical, and cellular effects of a preoperative five-day course of bexarotene in these patients before undergoing transsphenoidal surgery.
Timeline
- Start
- 2008-11
- Primary completion
- 2011-12
- Completion
- 2011-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Bexarotene | Small molecule | 300 mg/m2 | — |