drugset

drugset / Trial / NCT00845728

Exacerbation Study

NCT00845728 ↗

Phase 3 Completed 3439 enrolled Novartis Pharmaceuticals

RandomizedParallel-groupQuadruple-blindTreatment

Summary

This study compares indacaterol with tiotropium in terms of bronchodilation over 52 weeks

Timeline

Start: 2009-03
Primary completion: 2012-07
Completion: 2012-07

Publications

Decramer ML, Chapman KR, Dahl R, Frith P, Devouassoux G, Fritscher C, Cameron R, Shoaib M, Lawrence D, Young D, McBryan D; INVIGORATE investigators. Once-daily indacaterol versus tiotropium for patients with severe chronic obstructive pulmonary disease (INVIGORATE): a randomised, blinded, parallel-group study. Lancet Respir Med. 2013 Sep;1(7):524-33. doi: 10.1016/S2213-2600(13)70158-9. Epub 2013 Aug 21.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Indacaterol	Other / unclassified	150 ug	Inhaled
Comparator	Tiotropium	Other / unclassified	18 ug	Inhaled

Indications