drugset / Trial / NCT00848783

Irinotecan/Cisplatin, Potentially Curative Surgery With or Without Floxuridine, Followed by Capecitabine for Stomach and Gastro-esophageal Junction (GEJ) Cancers

NCT00848783

Phase 2 Terminated 8 enrolled NYU Langone Health
RandomizedParallel-groupOpen-labelTreatment

Summary

This study is to determine whether intraperitoneal (IP) Floxuridine is effective in the patients with advanced stomach or gastro-esophageal junction cancers in the treatment consisting of pre- and post-surgery chemotherapies.

Timeline

Start
2008-05
Primary completion
2011-08
Completion
2012-09

Drugs

EvaluationDrugModalityDoseRoute
Subject Floxuridine Unknown 3 g Other
Background Capecitabine Small molecule 2000 mg/m2 Oral
Background Cisplatin Other / unclassified 60 mg/m2 Intravenous
Background Irinotecan Small molecule 75 mg/m2 Intravenous