Relation of Metabolic Rate of Omeprazole and Eradication of Helicobacter Pylori Infection

Summary

The aims of this study are (1) to evaluate the prevalence rate of PM of CYP2C19 in our country; (2) to evaluate the efficacy of dual therapy with different dose of omeprazole and amoxicillin; (3) to judge the relationship of genotype of CYP2C19 and the eradication rate of dual therapy in the peptic ulcer patients; (4) to try to find out a predictor of success of dual therapy and an optimal dose of dual therapy as first-line and rescue anti-Helicobacter pylori regimen.

Timeline

Start

1996-08

Primary completion

1997-12

Completion

1998-02

Drugs

Indications