drugset / Trial / NCT00856375

NKTR-102 Versus Irinotecan in Patients With Second-Line, Irinotecan-Naïve, KRAS Mutant, Colorectal Cancer

NCT00856375

Phase 2 Completed 83 enrolled Nektar Therapeutics
RandomizedParallel-groupOpen-labelTreatment

Summary

This study will evaluate whether NKTR-102, an investigational drug has an anti-tumor effect in patients with colorectal cancer. This study will also evaluate how the safety and anti-tumor activity of NKTR-102 compares with irinotecan, a cancer drug that is approved for use in the US for treatment of patients with certain types of colorectal cancer.

Timeline

Start
2008-12
Primary completion
2014-07
Completion
2014-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Etirinotecan Pegol Other / unclassified Intravenous
Comparator Irinotecan Small molecule Intravenous

Indications