drugset / Trial / NCT00856375
NKTR-102 Versus Irinotecan in Patients With Second-Line, Irinotecan-Naïve, KRAS Mutant, Colorectal Cancer
RandomizedParallel-groupOpen-labelTreatment
Summary
This study will evaluate whether NKTR-102, an investigational drug has an anti-tumor effect in patients with colorectal cancer. This study will also evaluate how the safety and anti-tumor activity of NKTR-102 compares with irinotecan, a cancer drug that is approved for use in the US for treatment of patients with certain types of colorectal cancer.
Timeline
- Start
- 2008-12
- Primary completion
- 2014-07
- Completion
- 2014-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Etirinotecan Pegol | Other / unclassified | — | Intravenous |
| Comparator | Irinotecan | Small molecule | — | Intravenous |