drugset / Trial / NCT00857597
Endoscopic Fundoplication Versus Proton Pump Inhibitors for GERD Treatment
Phase 3
Terminated
60 enrolled
University of Pittsburgh
Crospon · collabEndoGastric Solutions · collabSandhill Scientific · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
The study objective is to evaluate the relative merits, safety and effectiveness of Transoral Incisionless Fundoplication (TIF) in GERD patients currently treated with daily Proton Pump Inhibitors (PPIs).
Timeline
- Start
- 2009-03
- Primary completion
- 2011-12
- Completion
- 2011-12
Outcome
Outcome not reported
Stopped: “Study was terminated after unplanned interim analysis of single centre data and results were reported”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Esomeprazole | Small molecule | — | — |
| Comparator | Lansomeprazole | Unknown | — | — |
| Comparator | Omeprazole | Other / unclassified | — | — |
| Comparator | Pantoprazole | Other / unclassified | — | — |
| Comparator | Rabeprazole | Small molecule | — | — |