drugset
drugset / Trial / NCT00861315

Pharmacokinetics of Nebulized Amikacin in Patients With Pneumonia Undergoing Mechanical Ventilation

NCT00861315 ↗

Phase 2/3 Unknown 24 enrolled Association Pour La Promotion A Tours De La Reanimation Medicale
RandomizedParallel-groupQuadruple-blindTreatment

Summary

Inclusion of patients undergoing mechanical ventilation and presenting a pneumonia in order to determine serum pharmacokinetics of nebulized amikacin. The primary aim is to determine the dose of amikacin to be nebulized in order to observe amikacin serum concentrations close to but inferior to those observed after standart intravenous amikacin infusion.

Timeline

Start
2009-01
Primary completion
2011-01
Completion
2011-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Amikacin Small molecule 20 mg/kg Inhaled
Subject Amikacin Small molecule 60 mg/kg Inhaled
Subject Amikacin Small molecule 80 mg/kg Inhaled
Subject Amikacin Small molecule 100 mg/kg Inhaled

Indications

No indication recorded.