drugset / Trial / NCT00870519

Brain Imaging Study in Subjects With Alzheimer Disease in Comparison to Healthy Subjects

NCT00870519 ↗

Phase 1 Terminated 2 enrolled Institute for Neurodegenerative Disorders
Non-randomizedParallel-groupOpen-labelDiagnostic

Summary

The underlying goal of this study is to assess 123-I MNI-168 SPECT imaging as a tool to detect ß-amyloid deposition in the brain of Alzheimer's Disease (AD) research participants and similarly aged and gender matched healthy subjects.

Timeline

Start
2009-01
Primary completion
2010-12
Completion
2010-12

Outcome

Outcome not reported

Stopped: “Assessment of data shows inadequate brain uptake, suggesting the tracer is inadequate as an imaging biomarker of brain amyloid.”

Drugs

EvaluationDrugModalityDoseRoute
Subject I-123-MNI-168 Diagnostic / imaging agent 185 mbq Other

Indications