drugset / Trial / NCT00874562
Rapamycin in Relapsed Acute Lymphoblastic Leukemia
Phase 1
Completed
6 enrolled
Dana-Farber Cancer Institute
Boston Children's Hospital · collabBrigham and Women's Hospital · collabNational Cancer Institute (NCI) · collab
RandomizedParallel-groupOpen-label
Summary
This is a research study designed to look at the biological effects of two drugs on leukemia cells. In this study, we are comparing the effects of drugs called corticosteroids when used alone or with another drug called rapamycin. Rapamycin is a drug that prevents the body's immune system from working normally. It has been used for many years after kidney transplants to prevent rejection of the organ. Recent work suggests that rapamycin may also help treat leukemia and other cancers.
Timeline
- Start
- 2007-07
- Primary completion
- 2009-11
- Completion
- 2016-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Sirolimus | Small molecule | — | Oral |